A couple of months ago, Laura and I both sent off tubes of spit so that "23andme" could analyze our respective DNA. It took me two tries, I'm afraid: I had eaten a cherry tomato from the garden right before my first sample*, and the results said that most of my ancestors were from the nightshade family. That didn't seem to represent my whole story. So I had to send off another ptooey of saliva.
If you haven't seen what 23andme is up to, you are missing quite a party. They have located 988 of my relatives so far, for one thing. They live all over the globe, and clearly have an inherited fondness for travel. I'm anxious about what this could lead to -- what if they want to see Farmington, Connecticut? Our house is pretty big, but the toilets can handle only so much.
There's a staggering amount of health-related information at 23andme. They can tell you what your risks are for various illnesses, how likely you are to tolerate an assortment of medicines, what kind of earwax you have (so that's what that stuff is!) and whether you have inherited a tendency to gather lint in your navel. Okay, I made that one up, but I'm telling you, I will not be surprised if someone is looking closely at that.
There are a bunch of illnesses the risks for which they can predict with strong confidence. Two of them --Alzheimer's and Parkinson's -- are under cyber lock and key. You have to keep telling them you're sure you want to know about those two. They don't want to shock you -- if you had a genetic tendency toward atrial fibrillation or high blood pressure, that could be one tragic scene, right? So it's: If you're sure, click here. Are you really sure? Click here. I'm telling you, the suspense builds like crazy.
Finally you reach a page where they've hidden your Alzheimer's and Parkinson's results (and a winky face saying "made ya look!").
All in all, there are more lower-than-average than higher-than-average risks for me, despite increased risks of Parkinson's, gout, Type 2 diabetes, and-- hold onto your hats -- breast cancer.
Two other things in 23andme have grabbed my attention. First is that my genome places me in the 97th percentile for Neanderthal genes. Let's let that sink in for a moment. I have more Neanderthal in me than 97% of the human population. This explains so much, and I anticipate that I will from here forward feel somewhat vindicated when I walk into a room and can't remember what I was going to do. That used to happen to my ancestors all the time.
The finding helps me make sense of that educational testing I had as a child, which indicated that I am an overachiever, performing beyond my actual, measurable abilities. I do more than I am actually capable of. That idea alone is, of course, a bit over my head. But now we know how true it is. Oog, as my kin used to say, furrowing their gigantic brows in vague understanding.
23andme can also tell you how short your telomeres have become. You want nice, long telomeres, since they erode with time and age, and shorter ones mean a decreasing ability for your cells to replicate nicely. Hence, we end up wrinkly and saggy (well, we Neanderthals do, anyway -- I can't speak for the rest of you). And eventually old, in the truest sense of the word. My telomeres are unusually shortened, likely from chemo -- the gift that keeps on giving. Mine are as short as someone who is 7.82 years older. This means my birthdate might as well have been January 3, 1948, making me almost a year older than my parents' firstborn, whom I now, given my aged telomeres, think of as my kid brother, Lee.
A note about Laura: her ancestors are white. White white white, man. They built the original suburbs in Northern Europe and still live either there or in Greenwich, Connecticut. Apparently hardly any of them were attracted to Neanderthals -- which stings a bit, I have to say.
*I trust you'll excuse this error in light of my ancestry.
Saturday, October 26, 2013
Sunday, October 20, 2013
gluten intolerance
I've sometimes thought that writers who drink -- think Hemingway as a classic example - do so because they kind of like feeling a bit depressed; drinking helps them lean toward their sadness in order to access deeper emotions so they can write. For them, drink is a catalyst between the gluten of depression and the yeast of creativity; it allows them to cook up some tasty writing. I'm not including alcoholics in this line of thinking, by the way -- just people looking to loosen their noggins.*
I know the creative momentum that comes with feeling sad. When I was in the thick of cancer and all that, I couldn't stop writing. Mild melancholy and moderate struggle are useful for getting a spark of inspiration going; witness much of the great poetry, great music, great road trips, great howls at the moon.
But it has to be mild melancholy. It doesn't work when you're lost in the darkest cave. Creativity can kick in, though, when the light is dim and there is a bit of cave-y feeling, like a fort around the lower bunk bed.
You need some catalyst for creative juices to flow, but I want that to come from light, not from darkness. I know you need both elements -- for contrast and depth perception -- but still.
I will admit to the thought that if I did get sick again, the upside is that I could write. Those of you who write, too, will forgive me for that terrible, fleeting notion. Yes, it seems I can write a bang up eulogy, but who wants grief as their muse? Not I.
So much better is when I am amused and feeling up. That happens more routinely when Laura is around: she is my muse and, god bless her, my amusement; my own mind-altering catalyst. With her away most of the time, my creative mind gets kind of dense -- no yeast; just gluten.
We've been talking about this when she is home, and we're trying to figure out how I can find some leavening within, so I can write.
But this feels ridiculous to me: too quiet a life to be creative? Tell that to Thoreau. You can bet he wasn't walking into town to pick up a six-pack of Bud to get his writing groove on.
I know the creative momentum that comes with feeling sad. When I was in the thick of cancer and all that, I couldn't stop writing. Mild melancholy and moderate struggle are useful for getting a spark of inspiration going; witness much of the great poetry, great music, great road trips, great howls at the moon.
But it has to be mild melancholy. It doesn't work when you're lost in the darkest cave. Creativity can kick in, though, when the light is dim and there is a bit of cave-y feeling, like a fort around the lower bunk bed.
Now, as I sit here with an impulse to write and no muse in sight, it's clear to me that writers who drink or get high are just cheating. They're stuck, and they know that if they can get themselves into an altered state of mind, cerebral ice jams will break apart. Hemingway was no different from the kids who share each other's Adderall and then find they've written a darned good history paper, by gum. Or people who indulge in cannabis and finally get traction on that essay when they speak from the perspective of their cat.
Me, I'll occasionally have we what call a "girl beer" -- example du saison being ginger beer -- but not more than one. That single serving has never inspired anything other than a good burp or two, and I'm not game for going beyond that. I confess that I am both jealous and judging of those who allow themselves to cheat and hot-wire their imaginations with substance.You need some catalyst for creative juices to flow, but I want that to come from light, not from darkness. I know you need both elements -- for contrast and depth perception -- but still.
I will admit to the thought that if I did get sick again, the upside is that I could write. Those of you who write, too, will forgive me for that terrible, fleeting notion. Yes, it seems I can write a bang up eulogy, but who wants grief as their muse? Not I.
So much better is when I am amused and feeling up. That happens more routinely when Laura is around: she is my muse and, god bless her, my amusement; my own mind-altering catalyst. With her away most of the time, my creative mind gets kind of dense -- no yeast; just gluten.
We've been talking about this when she is home, and we're trying to figure out how I can find some leavening within, so I can write.
But this feels ridiculous to me: too quiet a life to be creative? Tell that to Thoreau. You can bet he wasn't walking into town to pick up a six-pack of Bud to get his writing groove on.
I will say that I am a little hungry and thirsty after this post. Could be a good sign.
*Here I pause for a few minutes to google the relationship between eggnog and noggin -- a mighty close one which you will need to investigate on your own. I'm talking etymology, not ingestion.Friday, October 4, 2013
self-monitoring scales
There are several ways to find out if you are a high self-monitor or a low self-monitor. There's drawing a capital E on your forehead, of course. If your frame of reference is inside your head (low self-monitor), you'll draw it backwards from the perspective of the rest of the world. And if your frame of reference is the point of view of others (high self-monitor), you'll draw them a nice, legible E. Or, if you ever find yourself in a room that's built to be tilted and scientists ask you to hang a painting straight (they provide the painting), as a low self-monitor you will hang it according to your sense of what straight feels like, in reference to your own sense of relation to the earth; high self-monitors want the painting to match the off-kilter room.
Something like that. I am less clear on the details of the painting-hanging test, never having had the opportunity to hang a painting, upon the request of scientists, in a tilted room. I wish.
Overall, there seem to be a number of social advantages to being a high self-monitor. You tend to be better at getting people to like you, to listen to you, not to yell at you for getting in their way. You tend not to get in their way in the first place. You can shift, say, from the particular approach required for connecting to a 4-year-old, then manage a classroom of adolescents, then goof off with your family. You believe that Biblical thing about how you once spake as a child and now you've put away childish things, but you also know it's more complicated than that.
But if you're too far into the high self-monitoring end of things, you're a terrible show off, or -- so much worse -- you're slick, and people smell something phony about you. You walk down the busy street wondering if you look good, look right for the occasion. You shape-shift for each conversation and you sort of lose track of who you are outside of the expectations of others.
If you're too deep into the low self-monitoring end of things, you pick your nose and scratch your crotch as you walk down that street, forgetting that there is an art to hiding such things, the first involving strategic, casual gestures and the second involving strategic, casual use of pockets.
Most psychiatric patients tend to be very low self-monitors. Sociopaths, though, are too high. You with me?
Most of the rest of us are high self-monitors in peculiar ways, and way low in others. I, for example, kicked a black walnut for 3 miles today, absorbed in the challenge of keeping track of it among the autumn leaves and paying attention to cars as hazards but not caring about the possible judgment about what I was doing. That said, when the walnut crossed the street and many cars were parked at the light, I mimed, practiced as I am in such artistry, that I was crestfallen with my bad aim. I just kind of let my shoulders drop and my head fall. This communicated, "I may be kicking this walnut every 15 feet for a very long time, but you can see that I am sane. I am just really working on something here."
(If you have ever been walking in one direction with other people around and then needed to turn and go back to your car, chances are you have mimed "Oops. Oh, my. I have forgotten something! Is it in this pocket? Is it in this one? Oh, dear! [perhaps a small stomp or huff would be good here] I am going to turn around, but you can see I am not a crazy person, because clearly I have (which is so unlike me!) forgotten something." You know what you do when no one is around? You just turn around. Nary a stomp or huff.)
Still, by and large, in lots of the usual senses of self-monitoring, I tend toward the low end. I am either generally oblivious, rebellious, or too happy to care what you think. Few would accuse me of being slick. I think we can say that.
That said, I have islands of absurdly heightened self-monitoring. Sometime in the mid-1990s, I got my first car with an automatic transmission. For months as I drove I tried to make it look like I was still shifting gears. Pulling away from stoplights, I'd drop my right hand toward where the gearshift used to be to give people in other cars, all of whom were looking into my car to see whether I was noble or corrupt, the illusion that I was shifting gears. Sometimes I'd even move my hand down, then up and toward the right, then down to the right. Ahhh...I think I'll just stay in 4th gear for awhile.
Your judgment of how I look is not much of a priority for me, but apparently your judgment of my goodness is. That I preferred the ease of an automatic transmission to the more ecological stick-shift was a selfish, indulgent choice. It's called "standard" for a reason, and I failed it.
And when I walk by that piece of litter while you drive by, I assume you are wondering why I don't pick it up. So I often do, and I think, from the summit of high self-monitoring: "Note the Noble Soul Picking up Litter, Ye, Drivers on Main Street." Holding the Slurpee container with two fingers (the other digits extended and spread, so as to make it clear that the Slurpee container is litter I am nobly picking up, not something I would actually drink), I kick the walnut again. It shoots straight down the center of the sidewalk. I know no one is watching me make that perfect shot, but I think they are watching me carry the Slurpee container.
This self-monitoring thing: it's more complicated than the E on the forehead. I can't say if the painting-hanging exercise nails you one way or another, but I'd love to try, if you know of a tilted room that needs decorating. Can I bring my walnut?
Something like that. I am less clear on the details of the painting-hanging test, never having had the opportunity to hang a painting, upon the request of scientists, in a tilted room. I wish.
Overall, there seem to be a number of social advantages to being a high self-monitor. You tend to be better at getting people to like you, to listen to you, not to yell at you for getting in their way. You tend not to get in their way in the first place. You can shift, say, from the particular approach required for connecting to a 4-year-old, then manage a classroom of adolescents, then goof off with your family. You believe that Biblical thing about how you once spake as a child and now you've put away childish things, but you also know it's more complicated than that.
But if you're too far into the high self-monitoring end of things, you're a terrible show off, or -- so much worse -- you're slick, and people smell something phony about you. You walk down the busy street wondering if you look good, look right for the occasion. You shape-shift for each conversation and you sort of lose track of who you are outside of the expectations of others.
If you're too deep into the low self-monitoring end of things, you pick your nose and scratch your crotch as you walk down that street, forgetting that there is an art to hiding such things, the first involving strategic, casual gestures and the second involving strategic, casual use of pockets.
Most psychiatric patients tend to be very low self-monitors. Sociopaths, though, are too high. You with me?
Most of the rest of us are high self-monitors in peculiar ways, and way low in others. I, for example, kicked a black walnut for 3 miles today, absorbed in the challenge of keeping track of it among the autumn leaves and paying attention to cars as hazards but not caring about the possible judgment about what I was doing. That said, when the walnut crossed the street and many cars were parked at the light, I mimed, practiced as I am in such artistry, that I was crestfallen with my bad aim. I just kind of let my shoulders drop and my head fall. This communicated, "I may be kicking this walnut every 15 feet for a very long time, but you can see that I am sane. I am just really working on something here."
(If you have ever been walking in one direction with other people around and then needed to turn and go back to your car, chances are you have mimed "Oops. Oh, my. I have forgotten something! Is it in this pocket? Is it in this one? Oh, dear! [perhaps a small stomp or huff would be good here] I am going to turn around, but you can see I am not a crazy person, because clearly I have (which is so unlike me!) forgotten something." You know what you do when no one is around? You just turn around. Nary a stomp or huff.)
Still, by and large, in lots of the usual senses of self-monitoring, I tend toward the low end. I am either generally oblivious, rebellious, or too happy to care what you think. Few would accuse me of being slick. I think we can say that.
That said, I have islands of absurdly heightened self-monitoring. Sometime in the mid-1990s, I got my first car with an automatic transmission. For months as I drove I tried to make it look like I was still shifting gears. Pulling away from stoplights, I'd drop my right hand toward where the gearshift used to be to give people in other cars, all of whom were looking into my car to see whether I was noble or corrupt, the illusion that I was shifting gears. Sometimes I'd even move my hand down, then up and toward the right, then down to the right. Ahhh...I think I'll just stay in 4th gear for awhile.
Your judgment of how I look is not much of a priority for me, but apparently your judgment of my goodness is. That I preferred the ease of an automatic transmission to the more ecological stick-shift was a selfish, indulgent choice. It's called "standard" for a reason, and I failed it.
And when I walk by that piece of litter while you drive by, I assume you are wondering why I don't pick it up. So I often do, and I think, from the summit of high self-monitoring: "Note the Noble Soul Picking up Litter, Ye, Drivers on Main Street." Holding the Slurpee container with two fingers (the other digits extended and spread, so as to make it clear that the Slurpee container is litter I am nobly picking up, not something I would actually drink), I kick the walnut again. It shoots straight down the center of the sidewalk. I know no one is watching me make that perfect shot, but I think they are watching me carry the Slurpee container.
This self-monitoring thing: it's more complicated than the E on the forehead. I can't say if the painting-hanging exercise nails you one way or another, but I'd love to try, if you know of a tilted room that needs decorating. Can I bring my walnut?
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